Texas University working on HIV vaccine

Started by sajiv, Jun 22, 2009, 03:46 PM

previous topic - next topic
Go Down


Texas University working on HIV vaccine

HYDERABAD: There appears to be light at the end of the tunnel for those HIV-infected with virus causing AIDS.

A research team of the University of Texas is close to finding a "very good candidate" for developing a vaccine to stop the spread of the infection by stimulating cells to generate antibodies. "The time has come for translation of basic science to clinic," Sudhir Paul, director of the university's Clinical Immunology Research Centre, who heads the team, said.

The team's approach was innovative; it deviates from the rest of the field. The emphasis was on prevention through a region in the virus that is "quite constant" and useful for binding it to the cell. The team focused research on the covalent approach, rather than existing vaccines which are non-covalent in nature, to break the tolerance of the virus.

The method was adopted to see that the covalent vaccine, containing chemical extract, not only binds with the cell, but also ensures generation of more antibodies to prevent the spread of the virus. The approach was necessitated as the virus mutates rapidly and coupled with this was the immunity to the highly active retroviral therapies being used.

"Experiments have shown that we can break the tolerance and induce the cells to produce more antibodies that are broadly reactive to diverse strains so that the infection by all strains of the virus could be stopped," he told The Hindu. The process involves development of abzymes (from antibody and enzyme) which are monoclonal antibodies with catalytic activity for permanently breaking thousands of virus molecules, unlike the regular antibody that can be targeted at a single molecule.

As the experiments were met with success, efforts were on to take the candidate for testing in human beings, preferably on the infected and those resistant to drugs. "Development of covalent vaccine is a completely new approach and the process of developing the vaccine should not take more than a year, provided we have enough money and community support."

He admitted that there would be lot of resistance from scientists, but it was because science looks for proof.


this s the best idea to develop more medicine in HIV to cure more people in many countries

this is more important thing

Go Up

Quick Reply

With Quick-Reply you can write a post when viewing a topic without loading a new page. You can still use bulletin board code and smileys as you would in a normal post.

Warning: this topic has not been posted in for at least 120 days.
Unless you're sure you want to reply, please consider starting a new topic.

Note: this post will not display until it's been approved by a moderator.
Please leave this box empty:

Type the letters shown in the picture
Listen to the letters / Request another image

Type the letters shown in the picture:

shortcuts: alt+s submit/post or alt+p preview
IT Acumens Web Designing Chennai | GinGly :: Build your Personal Website | CineBuzz :: Cinema News | My Kids Diary :: Kids Memories Writing :: Book Website @ 349 Rs monthly
Copyright 2005 - 2020 :: IT Acumens :: All Rights Reserved. :: Sitemap
ITAcumens Discussion Forum with 2 lakhs post running for 15 years - Powered by IT Acumens Dedicated Server